DNA HP
deeply hydrating acid


Deep hydration. Visible renewal. Intelligent repair. There’s a few reasons why we use DNA HP in our skincare collection.

This polynucleotide, sourced sustainably from Alaskan salmon sperm, has a similar structure to human DNA which gives it an incredible ability to revitalise skin. It draws moisture into the skin, carrying 10 times more hydration than Hyaluronic Acid, that’s 10,000 times its weight in water - making it one of the most powerful hydrators in skincare. DNA HP also helps your skin produce collagen and elastin and, as a powerful antioxidant, it supports cell regeneration.

The result - plump, hydrated skin that glows

You’ll find DNA HP in nearly all our products - from our award-winning silver face cream to our luminous silver serum - working at a cellular level to enhance your skin’s structure, tone, and glow.

Discover our entire DNA HP skincare collection and curate your perfect routine.

What is DNA HP?


DNA HP (Hyper-Polymerised Deoxyribonucleic Acid) is a deeply hydrating acid sourced from sustainably-caught Alaskan salmon sperm - the same ingredient used in the popular salmon sperm facials. It’s one of the most effective active ingredients for hydration and cell repair in modern skincare.

DNA HP delivers water deep into the spaces between cells - where it’s most needed. It also helps prevent the breakdown of collagen, elastin and lipids in the skin, which contributes to its powerful anti-ageing and regenerating effects.

You may also see DNA HP referred to as Sodium DNA or HP DNA, but they’re all the same active ingredient.

What sets ARgENTUM’s DNA HP apart is that it’s kept in its purest form - unlike many lower-grade DNA products that are diluted with salt. This maximises cellular regeneration and DNA HP’s effectiveness in skincare.

Five benefits of DNA HP for the skin

Deep Hydration

DNA HP draws moisture deep into the space between cells and holds it there, helping skin feel plump, smooth, and deeply nourished.

Tightens & Firms

By protecting against elastase (an enzyme that breaks down collagen and elastin), DNA HP helps maintain firmness and reduce the appearance of fine lines.

Repairs & Regenerates

A potent polynucleotide, DNA HP helps stimulate skin cell renewal, encouraging your skin to heal and repair itself. This results in smoother, more even skin with a healthier tone and texture.

Antioxidant Defence

DNA HP’s antioxidant properties neutralise free radicals, defending your skin from environmental stress and preventing premature ageing.

Boosts Skin Resilience

By drawing in moisture and supporting skin repair, DNA HP keeps your skin stronger, more balanced, and able to handle whatever comes its way.

How to include DNA HP in your skincare routine

DNA HP pairs well with fellow antioxidants and soothing ingredients and is a wonderful addition to your daily routine.

Start with a gentle cleanser.
Clear away impurities with a cleanser that supports the skin barrier and allows DNA HP to absorb effectively.

Apply as a serum or moisturiser.
DNA HP is incredibly effective in leave-on formulas, such as serums and creams, so it can work all day. Try using it at night too, when your skin enters repair mode.

Seal with a nourishing oil.
Follow with a protective face oil to lock in hydration and support the skin barrier.

Finish with SPF.
Together, antioxidant DNA HP and SPF protect skin from environmental damage like UV-triggered oxidation.

Make it a ritual.
DNA HP delivers its best results with regular use. Integrate it daily to keep skin looking calm, hydrated, and visibly renewed.

How does DNA HP work on the skin?

DNA HP is uniquely powerful in its ability to hydrate and protect the skin.

It can carry 10,000 times its weight in water into the deepest layers of the skin – the space between skin cells – so skin stays plump and hydrated from within.

It also neutralises free radicals and protects against lipid peroxidation (the breakdown of skin lipids), one of the key causes of inflammation, loss of elasticity, and visible ageing. By supporting both hydration and repair, DNA HP helps skin stay resilient, youthful, and more even in tone and texture.

In our patented formulation, DNA HP also enhances the delivery of Silver Hydrosol - bringing its antibacterial and anti-inflammatory benefits beneath the skin’s surface for greater efficacy.

How to layer DNA HP ~ which ingredients to use and which to avoid

Layering DNA HP properly can amplify its skin-repairing and hydrating effects. Below are the ingredients it works well with, and a few that may require more care.

Pairs well with:

Silver Hydrosol
This soothing antibacterial works well with DNA HP, helping to deliver hydration and calm inflammation.

Ceramides
Strengthen the skin barrier, complementing the deep regenerative work of DNA HP.

Peptides
Help rebuild and strengthen the skin alongside the regenerative properties of DNA HP.

Use with caution:

High-strength AHAs/BHAs
These acids exfoliate the skin and can temporarily disrupt the barrier, reducing the hydrating effect of DNA HP or causing mild sensitivity.

Benzoyl Peroxide
Can oxidise actives and cause dryness when used with hydrating polymers like DNA HP.

Alcohol-heavy formulas
May counteract the hydrating benefits of DNA HP by stripping the skin.

Strong Vitamin C
The low pH of strong Vitamin C formulations may not be compatible with DNA HP and could lead to irritation.

As always, build your skincare ritual gradually and listen to how your skin responds. DNA HP is gentle, effective, and transformative when used with care.

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